Our Technology
20 years of fundamental research translated into revolutionary cosmetic solutions
Our detailed technological process
From skin sample to personalized recommendations: a revolutionary 5‑step process.
Skin sampling
Application of a biocompatible patch on the skin, painless and non-invasive, compatible with all skin types.
Biomarker collection
Patch processing to simultaneously extract proteins, metabolites, cells, and microbial DNA.
Rapid measurement of target molecules
Analysis using an aptamer biosensor.
AI analysis
Data processed by our AI models and proprietary algorithms to compute biological age and analyze the Hallmarks of Aging.
Personalized cosmetics
Automatic generation of tailor-made cosmetic recommendations based on the unique biological profile.
Personalized Scoring
Example of report and product recommendations generated by our AI
The 12 Hallmarks of Aging
Our technology quantifies the 12 fundamental mechanisms of aging identified by international scientific research.
Genomic Instability
Accumulation of DNA damage and dysfunction of cellular repair mechanisms.
Telomere Shortening
Progressive erosion of chromosome ends limiting the cell’s capacity to divide.
Epigenetic Alterations
Changes in methylation and acetylation patterns affecting gene expression.
Loss of Proteostasis
Dysfunction of protein quality control systems and accumulation of aggregates.
Nutrient Sensing Dysregulation
Alteration of metabolic signaling and nutrient-sensing pathways.
Mitochondrial Dysfunction
Decreased energy efficiency and increased oxidative stress.
Cellular Senescence
Permanent cell cycle arrest and secretion of pro-inflammatory factors.
Stem Cell Exhaustion
Reduction of the stem cell pool and its regenerative capacity.
Altered Intercellular Communication
Dysfunction of signaling between cells and chronic inflammation.
Chromatin Instability
Modifications in chromatin structure affecting gene accessibility.
Chronic Inflammation
Persistent low-grade inflammatory state characteristic of aging.
Microbial Dysbiosis
Alteration of microbiome composition and diversity.
Intellectual Property
Protection of our scientific and software innovation
Patent pending (DV 240022) – Molecular aging clocks for skin analysis – INSERM/UM – SATT AxLR
Exclusive algorithm protected by copyright
Competitive Advantage
How our technology compares to existing solutions on the market.
| Criteria | Skinomix | Existing solutions |
|---|---|---|
| Non-invasive | 100% | Limited |
| Speed | < 2 min | Hours |
| Accuracy | > 95% | Approximate |
| Personalization | Individual | Limited |
| Scientific basis | 12 Hallmarks | AI imaging / mono‑omics |
Competitive Advantages
Publications Scientifiques
Sélection de travaux 2025 dans des revues à fort impact. Cliquez pour lire la référence complète.
Associations of Skin Biomechanical Properties With Biological Aging Clocks and Longitudinal Changes in Intrinsic Capacity in Adults Aged 20–93: The INSPIRE‑T Project
W‑H Lu, S Guyonnet, J Raffin, S Bessou‑Touya, K Ravard Helffer, P Bianchi, J Le Digabel, P Bensadoun, JM Lemaître, P de Souto Barreto, B Vellas
A blood-based epigenetic clock for intrinsic capacity predicts mortality and is associated with clinical, immunological and lifestyle factors
M Fuentealba, L Rouch, S Guyonnet, JM Lemaitre, P de Souto Barreto, ...
Cross-sectional associations of epigenetic clocks with intrinsic capacity and functional ability in older adults with frailty and cognitive impairment: the COGFRAIL study
PL Valenzuela, JL Sánchez-Sánchez, P Bensadoun, JM Lemaître, ...
The associations between biological markers of aging and appetite loss across adulthood: retrospective case–control data from the INSPIRE-T study
A Turesson, A Koochek, M Nydahl, JM Lemaitre, P Bensadoun, ...